Whether your adult mesenchymal stem cells come from bone marrow or from fat probably does not make a difference in terms of clinical results. Although some centers claim that bone marrow derived cells are superior to fat derived cells, there is no evidence to substantiate this. The fact that there are many more studies on bone marrow cells does not prove clinical superiority but merely supports the fact that there are fewer studies using fat derived cells. It is important that one is not mislead by the word “bone” in bone marrow, possibly implying that since this is an “orthopedic source” it “might be better” for treating orthopedic conditions such as cartilage regeneration. In fact, the bone marrow is part of the reticulo-endothelial system and just happens to be found in the center of bone. All of these types of cells are equally primitive and have the potential to differentiate into mature functional tissues. More recent research for many disease types such as cardiac pathology, shows adipose derived cells appear to be superior to bone marrow derived cells. This may be related to the well documented qualitative and quantitative attrition in bone marrow stem cell counts related to age and chronic illness (chronic disease causes bone marrow suppression). Such changes in the number of cells over time and the quality of cells dependent on health have not been seen in fat derived stem cells. Fat derived cells are a natural choice for our investigational work considering their easy and rapid availability in extremely high numbers.
You have made an important decision to participate in research-based stem cell deployment. It’s exciting that these tools are now available for therapeutic use. Stem cell therapy with your own stem cells may very well be the next significant advance in medicine.
Patients have their fat harvested under local anesthesia using a completely sterile technique. This is performed in our state-of-the-art facility. The procedure lasts approximately twenty minutes, using specially designed equipment to harvest approximately 50cc of fat.
After harvesting the fat cells, the next step is to isolate the cells. This is accomplished by separating the fat cells and stem cells. The process utilized by Carolina Stem Cell Treatment Center yields extremely high numbers of viable stem cells.
Depending on the type of deployment required for your condition, stem cells can be injected directly into joints, subcutaneously, into spinal fluid, given intravenously or nebulized. All of these are considered minimally invasive methods of introducing the stem cells. Because it is your own DNA material, there is no rejection. The whole process takes less than three hours. There is little to no downtime afterwards.